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In hmolscience, manifold avenues refers to 
The following are related quotes:
- “The fascination of a growing science lies in the work of the pioneers at the very borderland of the unknown, but to reach this frontier one must pass over well traveled roads; of these one of the safest and surest is the broad highway of thermodynamics.”
- — Gilbert Lewis (1923), Thermodynamics and the Free Energy of Chemical Substances (pg. x)
- “Often in our more carefully cultivate gardens of thought some rank weed (Ѻ) grows with such vigor as to stunt the growth of the neighboring useful vegetables.”
- — Gilbert Lewis (1925), The Anatomy of Science (pg. 75)
- “All kinds of private metaphysics and theology have grown like weeds in the garden of thermodynamics.”
- — Erwin Hiebert (1966), “The Uses and Abuses of Thermodynamics in Religion”
- “The fact that a natural law is involved in every aspect of man’s behavior is so common that we would not expect the study of the influence of the entropy law on man’s economic actions to present any unusually complications. Yet manifold avenues open up almost as soon as one begins to tackle the problem.”
- “From my point of view, your entire program, while being well-meaning, I will give you that, is getting pretty sloppy. As you will find, when you begin to “tackle the problem”, as Roegen (1971) said, manifold avenues will begin to open up; and a large majority of these "avenues" (I consider each of the 5,376-articles I have penned online since 2007 to be a Roegen avenue), as I have found, end up in cul-de-sacs (dead ends), when travelling along the broad "highway of thermodynamics" (as Gilbert Lewis drove on at high speeds to great fame and eternal glory in the minds of many geniuses of the future).”
- Roegen, Nicholas. (1971). The Entropy Law and the Economic Process (pg. 3). Publisher.
- Glass wall (subdomain) – Hmolpedia 2020.